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The U.S. Food and Drug Administration reviewed Contrave on December 7, and approved the drug 13-7, stating the benefit of the drug outweighs the potential risk of a possible surge in blood pressure. Using two separate drugs to shed weight can be very effective you will find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the people that go through it one should err to the side of caution and permit the FDA do its job and demand some investigation be done so your public knows the side effects and dangers of the medications before we drive them. Keep in mind that drug companies will be in business to generate money and that they would say everything to keep people on their own medications. Researchers found out that participants taking this drug for any year, lost excess weight within four weeks and have kept the load off throughout the 56 weeks in the study. Contrave is really a combination of the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which might be made up of several active ingredient, which might make them more effective and safer. Combo-pilling could be the newest fad or even better the newest in the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular may be the fact that as of right now there are no long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures are a side effect with Contrave and must not be taken in people who have seizure disorders. The drug may also raise blood pressure levels and pulse rate, and mustn't be used in people with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must 't be used in patients with uncontrolled high blood pressure, in addition to by a person with heart-related and cerebrovascular (blood vessel dysfunction impacting your brain) disease. Patients using a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert health care professionals and patients towards the increased risk of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for stop smoking. Most of the combinations which might be used to enhance weight reduction involve an amphetamine and an antidepressant. Phentermine and Prozac can be a popular combination that have been around for a while, and although it has been around nobody wants to truly combine the 2 and try to get FDA approval to showcase it as a weight-loss pill. Right there should raise some red flags if the greedy pharmaceutical companies don't want to be involved in combining medications and selling them something must be wrong using the combination. In fairness there is one weight-loss combination pill that is in front of the FDA now Contrave?which couples naltrexone, accustomed to treat alcohol and abusing drugs, with the antidepressant bupropion (Wellbutrin, Zyban) it has been given the just do it to move forward by an FDA advisory committee, but by yet is not approved.